Acute Myeloid Leukemia Consolidation
Overview The treatment of acute myeloid leukemia (AML) is divided into two phases: remission induction and consolidation/maintenance. Remission induction chemotherapy is administered to produce a complete remission in the bone marrow. If a complete remission is achieved and no further therapy given, over 90% of patients will have a recurrence of disease in weeks to…
Relapsed Acute Myeloid Leukemia
Overview Patients with progressive or relapsed leukemia remain curable despite failing initial treatment. Patients failing initial treatment can be divided into two broad categories. Patients who fail to achieve an initial complete disappearance or remission of their cancer following two or more courses of remission induction chemotherapy are referred to as “induction failures.” Patients who…
Chronic Myeloid Leukemia
Overview Chronic myeloid leukemia (CML) is the abnormal growth of relatively mature myeloid (white blood) cells. Half of all patients with CML are diagnosed after the age of 67. CML is associated with a chromosomal abnormality in which genetic material from chromosome 9 is transferred to chromosome 22. The chromosome containing the genetic switch is…
Chronic Myeloid Leukemia Screening/Prevention
Overview Information about the prevention of cancer and the science of screening appropriate individuals at high-risk of developing cancer is gaining interest. Physicians and individuals alike recognize that the best “treatment” of cancer is preventing its occurrence in the first place or detecting it early when it may be most treatable. Chronic myeloid leukemia (CML)…
Blastic Phase
Overview Chronic myeloid leukemia (CML) is the abnormal growth of relatively mature myeloid (white blood) cells. Half of all patients with CML are diagnosed after the age of 67. CML is associated with a chromosomal abnormality in which genetic material from chromosome 9 is transferred to chromosome 22. The chromosome containing the genetic switch is…