Treatment of Advanced Stage IIB, III, IV Hodgkin Lymphoma
Patients classified as having stage III or IV disease with “A” or “B” symptoms, stage II disease and “B” symptoms, or bulky disease (site of disease greater than 10 centimeters) are all considered to have advanced stage Hodgkin’s lymphoma (HL). Chemotherapy treatment with ABVD (doxorubicin, bleomycin, Velban, and dacarbazine) for 6 cycles consistently cures a…
Treatment for Early Stage I – IIA Hodgkin Lymphoma
Patients classified as having stage I or IIA Hodgkin Lymphoma (HL) are considered to have early stage disease and are almost always curable. For the purpose of treatment selection patients can be segregated into two groups based on the presence of the following “higher risk” features. B symptoms (unexplained fever ≥38°C, soaking night sweats, unexplained…
Relapsed Hodgkin Lymphoma
Individuals who fail initial treatment for Hodgkin’s lymphoma (HL) remain curable using high dose chemotherapy (HDC) and autologous stem cell transplantation (ASCT), CAR T cells, and precision cancer medicines. The current dilemma is how best to use these therapies? Patients with relapsed or recurrent HL can be divided into two broad categories. Patients who fail…
Symptoms & Signs of Hodgkin Lymphoma
People with Hodgkin lymphoma most often first suspect a problem when they notice an enlarged lymph node. This typically manifests as a lump or swelling in the neck, armpit or groin region. Many patients have no additional symptoms. The most common symptoms caused by Hodgkin lymphoma include: Persistent painless swelling of lymph nodes in the…
Diagnosis & Tests for Hodgkin Lymphoma
Doctors use many tests to find, or diagnose, cancer. A biopsy is the only certain way to confirm a diagnosis of HL. When performing a biopsy, the doctor takes a sample of tissue for testing in a laboratory. It is important that the biopsy sample is large enough to allow the pathologist to make an…