Cancer News

Mouthwash reduces radiation-induced oral mucositis pain among patients with head and neck cancer (07/16/2019)

A mouthwash consisting of diphenhydramine, lidocaine and antacids significantly reduces oral mucositis pain when used in patients receiving radiation therapy for the treatment of head and neck cancer. Researchers assigned 275 patients with head and neck cancer being treated with an oral mucositis pain score > 3 to be treated with doxepin mouthwash or placebo... Continue Reading

FDA Approves Keytruda for First-line Treatment of Head and Neck Squamous Cell Carcinoma (06/13/2019)

FDA approves Keytruda for the first-line treatment of patients with metastatic or unresectable recurrent head and neck squamous cell carcinoma (HNSCC). Keytruda was approved for use in combination with platinum and fluorouracil (FU) for all patients and as a single agent for patients whose tumors express PD‑L1 (Combined Positive Score [CPS] ≥1) as determined by... Continue Reading

Nimotuzumab in Combination With Concurrent Radiotherapy and Cisplatin Is Active in Locally Advanced SCCHN (07/19/2018)

Nimotuzumab in combination with concurrent radiotherapy and cisplatin provides significant clinical benefits in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN). About Head and Neck Cancer Head and neck cancers include a number of different malignant cancers that develop in or around the throat, larynx (voice box), nose, sinuses and …

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University of Colorado Study Suggests new Combination Treatment for Head and Neck Cancer (06/14/2018)

The five-year survival rate for locally-advanced head and neck cancer is only 46 percent, even with treatments including surgery, radiation, chemotherapy and/or genetically targeted treatments such as cetuximab. Often, the problem is that while treatments initially work, cancer evolves to resist treatment. “The question has been how do cancers resist these treatments,” says Sana Karam, MD, PhD, …

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Managing Side Effects From EGFR Inhibitors (04/10/2018)

CancerConnect News: Epidermal Growth Factor Receptor (EGFR) inhibitor drugs are a type of precision cancer medicine commonly used to treat lung, colon, head and neck and other cancers that over express the EGFR.  There are several EGFR inhibitor drugs and these cause similar side effects. The EGFR pathway is a normal biologic pathway found in …

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Spring into Action For Oral, Head, and Neck Cancer Awareness Week! (04/03/2018)

CancerConnect News: As the month of April brings head and neck cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated head and neck cancer information throughout the year. According to statistics from the American Cancer Society (ACS), …

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Guidelines for Human Papilloma Virus Testing in Head and Neck Carcinomas (02/06/2018)

CancerConnect News:  The Centers for Disease Control and Prevention estimates that in the United States, there are more than 16,000 individuals diagnosed with Human Papilloma Virus (HPV)-positive OroPharyngeal Squamous Cell Carcinoma (OPSCC) each year and there has been a significant increase over the past several decades.  Patients with HPV-positive OPSCC tend to be younger males, …

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Depressive Symptoms Linked to Shorter Survival in Patients with Head and Neck Cancer (01/31/2018)

CancerConnect News:  In a study of patients with head and neck cancer, even mild depressive symptoms were associated with poorer overall survival according to a team of doctors from the University of Louisville who published their findings in Cancer the peer-reviewed journal of the American Cancer Society. Globally, head and neck cancer (HNC) comprises the …

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Head and Neck Cancer Patients at Risk of Cognitive Problems Following Treatment (01/08/2018)

CancerConnect News: Patients who survive head and neck cancer may be more likely to experience declines in mental function according to the results of a recent study. The findings are drawn from cognitive assessments for 80 survivors of head and neck cancer compared to a control group of 40 otherwise similar people who didn’t have …

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U.S. FDA Removes Clinical Hold on CEL-SCI’s Phase 3 Head & Neck Cancer Trial (08/21/2017)

CEL-SCI Corporation today announced it has received a letter from the U.S. Food and Drug Administration (FDA) stating that the clinical hold that had been imposed on the Company’s Phase 3 cancer study with Multikine* (Leukocyte Interleukin, Inj.) has been removed and that all clinical trial activities under this Investigational New Drug application may resume. …

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